Linear Antibiotic Selection Markers

Features & Benefits

• Use in cotransfection methods to establish stable cell lines
• Use less DNA for each transfection
• More positive clones result than when circular plasmid markers are used

Description

Linear Selection Markers are ideal for cotransfection with any expression vector where transfection stability is required. These markers are short, purified linear DNA fragments comprised of the marker gene, an SV40 promoter, and the SV40 polyadenylation signal.

Cotransfection of a Linear Selection Marker achieves a higher number of positive clones than using either a single response vector containing a selection marker, or cotransfecting with a circular selection marker (see additional information).

We offer Linear Selection Markers for either hygromycin or puromycin resistance.