EF-1 Alpha (EF1a) Promoter Vectors

Features & Benefits

• Constitutive mammalian promoter
• Good alternative for expression in cells with low CMV promoter activity

Description

Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used to drive ectopic gene expression in various in vitro and in vivo contexts.

EF-1 alpha (or EF1a) is often useful in conditions where other promoters (such as CMV) have diminished activity or have been silenced (as in embryonic stem cells).

EF-1 alpha promoter vectors are available in multiple formats for either plasmid or lentiviral delivery:

- Fluorescent protein fusion vectors
- IRES vectors for coexpression of 2 genes
- Vectors with either Myc- or HA-tags for protein purification