FasL-Strep Apoptosis Assays

  • Defined trimeric structure
  • High stability
  • Efficient apoptosis induction
  • Easy handling (detection,
  • immobilization, isolation)
  • via Strep-tag
In the heterogeneous apoptosis assay format, the FasL-Strep molecule is immobilized on Strep-Tactin® coated microplates. After addition of the cells to be investigated, caspase 3/7 activity is determined to measure the extent of apoptosis.
This FasL-Strep apoptosis assay is robust and reproducible due to the high stability of the FasL-Strep reagent. These properties identify this assay as an ideal basis for HTS assays for screening anti-apoptotic molecules.

The homogeneous FasL-Strep Apoptosis Assay can be performed in the presence of the anti-Strep-tag® antibody "StrepMAB-Immo" which increases apoptotic activity of FasL-Strep. The homogeneous FasL-Strep assay enables the quantitative determination of anti-apoptotic agents as shown by Fas-Fc competition. The measurement of apoptosis in the respective cells is achieved by determination of caspase 3/7 activity.

Ordering information

Westburg offers this product in The Netherlands, Belgium, Finland, Luxembourg, Denmark, Sweden, Norway, Iceland,
If you are not located in these countries please visit the IBA website to find your local distributor.
Cat no. Description
IB 2-3901-002 Human FasL-Strep 2.5µg
IB 2-3901-010 Human FasL-Strep 10µg
IB 2-3911-000 Heterogeneous FasL-Strep Apoptosis Assay, human 96assays
IB 2-3912-000 Homogeneous FasL-Strep Apoptosis Assay, human 96 assays
IB 2-3951-002 Mouse FasL-Strep 2.5µg
IB 2-3951-010 Mouse FasL-Strep 10µg
IB 2-3961-000 Heterogeneous FasL-Strep Apoptosis Assay, murine 96 assays
IB 2-3962-000 Homogeneous FasL-Strep Apoptosis Assay, murine 96assays