C57BI/6 mouse hepatocytes (TRL)
- Cryopreserved mouse hepatocytes
- High viability (>80%)
- Characterized for Phase I/II drug-metabolizing enzyme activity
Hepatocytes can be used for a variety of in vitro applications, including drug-drug interaction, drug transporter activity, and toxicity of drug candidates.
C57BI mouse hepatocytes are isolated by Triangle Research Laboratories (now part of Lonza) and characterized for viability, plateability (adherence to a collagen-coated surface), and general Phase I and Phase II drug metabolizing enzyme activities.
Suspension qualified cryopreserved mouse hepatocytes have post-thaw viabilities over 80%.
Plateable cryopreserved mouse hepatocytes have post-thaw viabilities over 80%. Each lot can also be plated in a collagen-coated plate or similar. These lots are guaranteed to maintain a healthy monolayer (>85% confluency) for a minimum of 3 days in culture.