Cynomolgus monkey hepatocytes (TRL)
- Cynomolgus monkey hepatocytes
- Fresh and cryopreserved formats
- High viability (>80%)
- Characterized for Phase I/II drug-metabolizing enzyme activity
- Characterized for plateability
TRL hepatocytes are isolated from Cynomolgus monkey and characterized for viability, plateability (adherence to a collagen-coated surface), and general Phase I and Phase II drug metabolizing enzyme activities.
These monkey hepatocytes are available in cryopreserved and fresh format. Fresh hepatocytes are also available plated in a monolayer.
Cryopreserved Cynomolgus monkey hepatocyes viability
Suspension qualified cryopreserved hepatocytes have post-thaw viabilities over 80%.
Plateable cryopreserved hepatocytes have post-thaw viabilities over 80%. Each lot can also be plated in a collagen-coated plate or similar. These lots are guaranteed to maintain a healthy monolayer (>85% confluency) for a minimum of 3 days in culture.
Fresh Cynomolgus monkey hepatocyes viability
Each lot of fresh monkey hepatocytes is tested before release to ensure that hepatocytes are high viability. The fresh hepatocytes in suspension are at least 80% viable and plated hepatocyte monolayers are at least 85% confluent.