COPD Airway Cells

  • Cells from patients with COPD
  • COPD lung fibroblasts
  • COPD bronchial epithelial cells
  • COPD bronchial smooth muscle cells

Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. Lonza's COPD Airway Cells include:

  • lung fibroblasts that are isolated from adult lung tissue,
  • bronchial epithelial cells are isolated from epithelial lining of airways above bifurcation of the lungs,
  • bronchial smooth muscle cells that are isolated from the major bronchia. 

COPD lung fibroblasts

Lonza's COPD Lung fibroblasts stain negative for von Willebrand factor VIII, cytokeratins 18 and 19, and alpha smooth muscle actin. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Recommended mediumFGM™-2 BulletKit™

COPD bronchial epithelial cells

Lonza's COPD Bronchial Epithelial cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

DHBE-COPD cells (cat. # LO 00195275S) are suitable for air-liquid interface studies and are guaranteed to promote full differentiation of the airway epithelium expressed by the formation of a polarized epithelium with good barrier function (transepithelial resistance), secretory phenotype (mucin secretion) and ciliogenesis. Differentiation usually will occur by day 22 in culture.

Recommended medium for growth of cellsBEGM™ BulletKit™

COPD bronchial smooth muscle cells

Lonza's COPD Bronchial Smooth Muscle cells stain negative for von Willebrand factor VIII, cytokeratins 18 and 19, and alpha smooth muscle actin. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Recommended mediumSmGM™-2 BulletKit™

Bronchial epithelial cells undifferentiated (C) and differentiated (D) stained with beta tubulin for cilia formation Bronchial epithelial cells undifferentiated (C) and differentiated (D) stained with beta tubulin for cilia formation

Ordering information

Westburg offers this product in The Netherlands, Belgium, Luxembourg,
If you are not located in these countries please visit the Lonza website to find your local distributor.
Cat no. Description
LO 00195275S DHBE-COPD, guaranteed for B-ALI
LO 195274 DBSMC-COPD (Diseased Bronchial Smooth Muscle Cells - COPD)
LO 195275 DHBE-COPD (Diseased Human Bronchial Epithelial Cells - COPD)
LO 195277 DHLF-COPD (Diseased Human Lung Fibroblasts - COPD )
LO CC-2934 D-SAEC (Diseased Small Airway Epithelial Cells – COPD), cryo