Advantage GC Polymerase Mix & Kits

  • Amplify sequences that are up to 90% GC
  • GC-Melt additive destabilizes GC-structures
  • Optimized mixes for cDNA and genomic DNA
Advantage-GC 2 amplifies troublesome GC-rich regions with ease. The Advantage-GC 2 System consists of an optimized enzyme mix, a buffer containing DMSO, and a special reagent called GC-Melt.

GC-rich regions are notoriously difficult to amplify. Sometimes adding DMSO can help, but when even that isn't enough, Advantage-GC 2 may do the trick. Advantage-GC 2 with GC-Melt effectively disrupts base pairing, allowing amplification of regions that are up to 90% GC. And because we provide GC-Melt in a separate tube, you can add it to the PCR master mix at the optimal concentration for your experiment.

The Advantage GC 2 Polymerase Mix is ideal for use with cDNA templates. For amplifying fragments of GC-rich mammalian genomic DNA, we recommend Advantage GC Genomic LA Polymerase Mix.

Ordering information

Westburg offers this product in The Netherlands, Belgium, Luxembourg,
If you are not located in these countries please visit the Clontech website to find your local distributor.
Cat no. Description
CL 639112 Advantage GC cDNA Polymerase Mix 100 rxns
CL 639114 Advantage GC 2 Polymerase Mix 100 rxns
CL 639115 Advantage GC cDNA PCR Kit 100 rxns
CL 639116 Advantage GC cDNA PCR Kit 10 rxns
CL 639119 Advantage GC 2 PCR Kit 100 rxns
CL 639120 Advantage GC 2 PCR Kit 10 rxns