Strep-Tactin XT Resin

  • Higher Strep-tag II binding affinity
  • Great for High-throughput screening, Batch purification, Denaturating conditions
  • More concentrated target protein
  • Higher protein yield

Strep-Tactin XT offers higher affinity

The new Strep-Tactin XT has a higher binding affinity to Strep-tag II and is more stable compared to the original Strep-Tactin. This enables new applications such as high-throughput screening, batch purification and denaturing purification.


Enhanced binding of Twin-Strep-tag-mCherry to Strep-Tactin XT compared to Strep-Tactin. A significant loss of mCherry occurred during the washing steps if Strep-Tactin is used for purification. In the case of Strep-Tactin®XT no target protein is lost during the purification procedure. Western blot analysis revealed that remaining impurities were degradation products of mCherry.

Higher yield

Strep-Tactin XT also provides higher protein yields compared to Strep-Tactin®. Together with an optimized elution profile this gives you more concentrated target protein. At the same time Strep-Tactin XT still has all the benefits of Strep-Tactin for protein purification:  very high purity (>95%), physiological buffer conditions and mild elution.

Ordering information

Westburg offers this product in The Netherlands, Belgium, Finland, Luxembourg, Denmark, Sweden, Norway, Iceland,
If you are not located in these countries please visit the IBA website to find your local distributor.
Cat no. Description
IB 2-4010-010 Strep-Tactin XT Superflow (50%) 20 ml
IB 2-4021-001 Strep-Tactin XT Superflow cartridge (with 10-32 connection for HPLC and Äkta) 1 x 1 ml
IB 2-4998-000 Strep-Tactin XT Starter Kit