Typically, standard cell culture is performed with the addition of 5-10% of serum, to keep the cells happy and alive. But have you ever asked yourself the question if serum is the best choice?
The known but often ignored disadvantages of serum
Serum has various disadvantages that can affect the consistency of your results that each scientist ought to know:
It contains numerous undefined factors
It has a high lot-to-lot variability
It has a high risk of contamination with infectious agents
It has a high risk of contamination with other interfering components
Due to these disadvantages, your cells can respond differently when compared to the exact same cells other groups are culturing. Differences can even occur in your own experiments due to serum batch variability, leaving you with non-reproducible results.
Eliminate your serum issues: choose serum-free media
Gain control over your culture conditions and eliminate all the issues that come along when culturing with serum. Serum-free media contain well-defined and consistent components. You can choose to completely switch to a complete serum-free medium that works best for your type of cells, or keep on using your medium but substitute your serum with a well-defined alternative. Your options are listed below.
Need help with switching to serum-free media? See our guidance and discount offer >>
Want to keep on using your medium, but substitute your serum? Choose our chemically defined substitute: