What is SPR?

Surface plasmon resonance (SPR) is an optical effect that can be utilized to measure the binding of molecules in real-time without the use of labels.

SPR instruments are primarily used to measure the binding kinetics and affinity of molecular interactions; it can be used to measure the binding between two proteins, a protein and an antibody, DNA and a protein, and many more.

SPR helps researchers determine which molecules interact, why they interact, and how strongly they interact.

Typical biomolecule binding curve generated with Nicoya's OpenSPR system Typical biomolecule binding curve generated with Nicoya's OpenSPR system

An expert's guide to surface plasmon resonance

Surface plasmon resonance (SPR) is the most commonly used technique to determine accurate binding kinetics.

Download our free ebook to:

  • Learn the ins and outs of surface plasmon resonance technology
  • Get the best tricks for optimizing binding kinetics
  • Become an SPR expert with simple diagram-supported explanations
 
Download the free SPR E-Book